From Birnam Designs Wiki

Wine 1.1.12 added sub-pixel font rendering. But you might not even see normal font antialiasing if the registry isn't set right!

In regedit: HKEY_CURRENT_USER\Control Panel\Desktop] <geshi lang=DOS> "FontSmoothing" = "2" "FontSmoothingType" = dword:00000002 "FontSmoothingGamma" = dword:00000578 "FontSmoothingOrientation" = dword:00000001 </geshi>

The FontSmoothingType can be:

0 - none 1 - normal antialiasing 2 - subpixel antialiasing